Technology

CoreEncapsulation technology essentially deals with the incorporation of commercially available active material into protective system that can deliver the active to specific site.

Skin, hair and mucosal surfaces are useful targets for the delivery of active compounds.

The core is covered by solid shell which is used to deliver, protect stabilize or control the release of the core/active

Protective Shell

  • ShellUsually selected from a list of materials “generally regarded as safe” (GRAS) to meet the
    needs of the application as well as regulatory demands e.g.. Biodegradability
  • USP Grade
  • Suitable for personal care use

Core

  • CorenewIngredients
  • encapsulated include
  • colors, fragrances, flavors, vitamins & oils etc.

Target Delivery

Target DeliverySkin, hair and mucosal surfaces are useful targets for the delivery of active compounds.

Level of Incorporated active

  • Level of ActiveWill depend upon the nature of the active ingredients being encapsulated.

Reasons to employ an encapsulation:

  • Reason EncapsSuperior handling of active material (e.g. conversion of liquid active agent into a powder).
  • Improved stability in fnal products during processing (e.g. less evaporation of volatile active).
  • Creation of visible effects.
  • Adjustable properties of active components (particle size, structure, oil or water soluble color.
  • Off taste masking.
  • Controlled release.

Types of Encapsulated Spheres

  • Encapsulated SpheresPressure release / burst release / water penetration control system.
  • This is design as water as the main agent controlling the release of the active.
  • In this system active molecules cannot physically diffuse out the device without water molecule diffusing in
  • This is usually achieved by incorporating actives in hydrophilic polymer that is stiff when dry but swells when placed in aqueous environment.

    Spheres ph1pH Responsive Spheres.
  • In this technique Spheres are coated with ionic pH sensitive polymers having as main feature that they release protons
    in response to pH change.
  • Having a structure acid or basic groups that can accept or release protons in response to pH change in surrounding
    environment.

    Color SpheresColor in color Spheres.
  • These Spheres gives color changing effect on rubbing.
  • Color in color Spheres is a simple concept where in the core is of one color and the out shell can be of different color.
  • The process consists essentially of spraying a color solution fluid on to particles of substrate material undergoing encapsulation.
  • This is achieved by fluid bed coating.

    Oil EncapsulationOil encapsulation.
  • The encapsulation method provided Spheres where oil droplets were well dispersed and protected.
  • The wall material used commonly includes synthetic polymer and natural biomaterials (usually carbohydrates).

    Flavor EncapsulationFlavor and Fragrance Encapsulation
  • Encapsulation of flavor and fragrance in dedicated shell.
  • It can limit the degradation or loss of the flavor during the various product process and storage.
  • The shell can also provide the functional properties such as control release of aromatic molecules in given environment.

Film Casting

  • Film CastingFilms are hydrophilic and temperature sensitive in nature.
  • It dissolve upon contact with wet surface such as tongue within few seconds.
  • We can encapsulate oil and color in various attractive shapes.

Extrustion
Extrustion
Drug Layering
Drug Layering
Fluid Bed Multiprocessor
Fluid Bed Multiprocessor
Integrated Extruder Spheronizer
Integrated Extruder Spheronizer

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